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課程名稱 |
動物基因轉殖與複製技術
TRANSGENIC AND CLONING TECHNOLOGY IN ANIMAL |
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開課學期 |
97-2 |
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授課對象 |
生物資源暨農學院 生物科技研究所 |
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授課教師 |
宋麗英 |
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課號 |
Biot8005 |
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課程識別碼 |
642ED0060 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期二2,3,4(9:10~12:10) |
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上課地點 |
生技所410 |
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備註 |
本課程以英語授課。
限博士班
總人數上限：10人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
COURSE OUTLINES AS FOLLOWING:
PART I : TRANSGENIC ANIMALS
1. INTRODUCTION OF TRANSGENIC ANIMALS
2. GENERATION OF TRANSGENIC ANIMALS
3. FACTORS OF AFFECTING TRANSGENIC ANIMAL PRODUCTION
4. TRANSGENIC ANIMAL MODEL SYSTEM
5. APPLICATIONS OF TRANSGENIC FARM ANIMALS
PART II: SOMATIC CELL NUCLEAR TRANSFER (SCNT) IN ANIMAL
6. AN OVERVIEW OF STRATEGIES TO INDUCE EPIGENETIC REPROGRAMMING
7. INTRODUCTION OF NUCLEAR REPROGRAMMING BY SOMATIC CELL NUCLEAR TRANSFER
8. SOMATIC NUCLEAR TRANSFER IN RODENT SPECIES
9. SOMATIC NUCLEAR TRANSFER IN DOMESTIC ANIMAL SPECIES
10. INTERSPECIES NUCLEAR TRANSFER (INT) AND ITS IMPLICATIONS FOR EMBRYONIC STEM CELL BIOLOGY
11. EPIGENETIC REGULATION IN CLONED EMBRYO DEVELOPMENT
12. DERIVATION AND CHARACTERIZATION OF ESCS FROM CLONED EMBRYOS
13. APPLICATIONS OF CLONING, REPRODUCTIVE VS. THERAPEUTIC CLONING
14. ETHICAL CONCERNS OF ANIMAL CLONING AND EMBRYONIC STEM RESEARCH |
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課程目標 |
ANIMAL TRANSGENESIS AND NUCLEAR TRANSFER (NT) TECHNOLOGY ARE POWERFUL TOOLS FOR UNDERSTANDING THE CELLULAR AND MOLECULAR ASPECTS OF GENE EXPRESSION IN EMBRYO DEVELOPMENT. THIS COURSE WILL PROVIDE STUDENTS A STATE OF THE ART OF ANIMAL TRANSGENESIS AND SOMATIC CELL NUCLEAR CLONING, AS WELL AS ITS APPLICATIONS. STUDENTS WILL BE ASKED TO PRESENT IN PARTICULAR TOPIC THEY WERE ASSIGN AFTER EXTENSIVE REVIEW AND DISCUSSION. GUEST SPEAKERS WILL PLAN TO INVITE FOR THE LECTURES AS NECESSARY. |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
1.IAN R. GORDON, REPRODUCTIVE TECHNOLOGIES IN FARM ANIMALS. 2004. CABI PUBLISHING, CABI INTERNATIONAL, WALLINGFORD, OXFORDSHIRE, UK
2.PAUL J. VERMA AND ALAN O. TROUNSON, NUCLEAR TRANSFER PROTOCOLS-CELL REPROGRAMMING AND TRANSGENESIS, HUMANA PRESS, TOTOWA, NEW JERSEY, USA
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評量方式
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